Pediatric colon cancer can be prevented by screening, detecting dysplasia


07 October 2023

watch 4 minutes


Source/Disclosure

Source:

Gomez-Esquivel Rd. Colorectal cancer screening in pediatric IBD: That’s one thing. Presented at: Naspaghan; October 4-7, 2023; San Diego.


Disclosures: Gomez-Esquivel has made no relevant financial disclosures.


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In Helio exclusive video, Rene D. Gomez-Esquivel, MD, From his presentation at the 2023 NASPGHAN Annual Meeting, risk factors for pediatric colon cancer as well as best practices for screening and resection of the lesion were discussed.

“Colon cancer is the most common solid tumor of the GI tract in pediatrics,” said Gomez-Esquivel, MD, associate professor of medicine and pediatrics at the Morsani College of Medicine at the University of South Florida. “The problem with pediatric cancer compared to adult colon cancer is that pediatric patients tend to have more advanced disease when they are diagnosed. Pediatric colon cancer can be prevented if you get screened for and treat dysplasia.

Gomez-Esquivel said risk factors for pediatric colon cancer include inflammatory bowel disease and with global cases of pediatric IBD “continuing to increase over the past few years,” it is important to monitor patients with colon cancer.

These patients should be screened when they have had IBD for at least 8 years or soon after the diagnosis of primary sclerosing cholangitis, with a recommended screening interval between 7 and 10 years. Once the inflammation is controlled, screening should be done to maximize detection of lesions, he said.

When dysplasia is identified, the lesions should be removed via endoscopic mucosal resection or endoscopic submucosal dissection.

“Once we do that, we can prevent colon cancer in this population of pediatric patients,” Gomez-Esquivel said.

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